Overexpression of LIMK1 in hippocampal excitatory neurons improves synaptic plasticity and social recognition memory in APP/PS1 mice

Accumulating evidence indicates that the actin regulator cofilin is overactivated in Alzheimer’s Disease (AD), but whether this abnormality contributes to synaptic and cognitive impairments in AD is unclear. In addition, the brain region and cell types involved remain unknown. In this study, we spec...

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Dades bibliogràfiques
Publicat a:Mol Brain
Autors principals: Zhang, Haiwang, Ben Zablah, Youssif, Liu, An, Lee, Dongju, Zhang, Haorui, Meng, Yanghong, Zhou, Changxi, Liu, Xingde, Wang, Yiming, Jia, Zhengping
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2021
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8314529/
https://ncbi.nlm.nih.gov/pubmed/34315506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-021-00833-3
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