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Excitability and Synaptic Alterations in the Cerebellum of APP/PS1 Mice

In Alzheimer's disease (AD), the severity of cognitive symptoms is better correlated with the levels of soluble amyloid-beta (Aβ) rather than with the deposition of fibrillar Aβ in amyloid plaques. In APP/PS1 mice, a murine model of AD, at 8 months of age the cerebellum is devoid of fibrillar A...

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Detalhes bibliográficos
Main Authors: Hoxha, Eriola, Boda, Enrica, Montarolo, Francesca, Parolisi, Roberta, Tempia, Filippo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325253/
https://ncbi.nlm.nih.gov/pubmed/22511962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034726
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