Overexpression of LIMK1 in hippocampal excitatory neurons improves synaptic plasticity and social recognition memory in APP/PS1 mice

Accumulating evidence indicates that the actin regulator cofilin is overactivated in Alzheimer’s Disease (AD), but whether this abnormality contributes to synaptic and cognitive impairments in AD is unclear. In addition, the brain region and cell types involved remain unknown. In this study, we spec...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Brain
Prif Awduron: Zhang, Haiwang, Ben Zablah, Youssif, Liu, An, Lee, Dongju, Zhang, Haorui, Meng, Yanghong, Zhou, Changxi, Liu, Xingde, Wang, Yiming, Jia, Zhengping
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2021
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8314529/
https://ncbi.nlm.nih.gov/pubmed/34315506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-021-00833-3
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