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An optogenetic method for interrogating YAP1 and TAZ nuclear–cytoplasmic shuttling

The shuttling of transcription factors and transcriptional regulators into and out of the nucleus is central to the regulation of many biological processes. Here we describe a new method for studying the rates of nuclear entry and exit of transcriptional regulators. A photo-responsive LOV (light–oxy...

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Détails bibliographiques
Publié dans:J Cell Sci
Auteurs principaux: Dowbaj, Anna M., Jenkins, Robert P., Williamson, Daniel, Heddleston, John M., Ciccarelli, Alessandro, Fallesen, Todd, Hahn, Klaus M., O'Dea, Reuben D., King, John R., Montagner, Marco, Sahai, Erik
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists Ltd 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8313864/
https://ncbi.nlm.nih.gov/pubmed/34060624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.253484
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