An optogenetic method for interrogating YAP1 and TAZ nuclear–cytoplasmic shuttling

The shuttling of transcription factors and transcriptional regulators into and out of the nucleus is central to the regulation of many biological processes. Here we describe a new method for studying the rates of nuclear entry and exit of transcriptional regulators. A photo-responsive LOV (light–oxy...

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Bibliographic Details
Published in:J Cell Sci
Main Authors: Dowbaj, Anna M., Jenkins, Robert P., Williamson, Daniel, Heddleston, John M., Ciccarelli, Alessandro, Fallesen, Todd, Hahn, Klaus M., O'Dea, Reuben D., King, John R., Montagner, Marco, Sahai, Erik
Format: Artigo
Language:Inglês
Published: The Company of Biologists Ltd 2021
Subjects:
Tools and Resources
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8313864/
https://ncbi.nlm.nih.gov/pubmed/34060624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.253484
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