An optogenetic method for interrogating YAP1 and TAZ nuclear–cytoplasmic shuttling

The shuttling of transcription factors and transcriptional regulators into and out of the nucleus is central to the regulation of many biological processes. Here we describe a new method for studying the rates of nuclear entry and exit of transcriptional regulators. A photo-responsive LOV (light–oxy...

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發表在:J Cell Sci
Main Authors: Dowbaj, Anna M., Jenkins, Robert P., Williamson, Daniel, Heddleston, John M., Ciccarelli, Alessandro, Fallesen, Todd, Hahn, Klaus M., O'Dea, Reuben D., King, John R., Montagner, Marco, Sahai, Erik
格式: Artigo
語言:Inglês
出版: The Company of Biologists Ltd 2021
主題:
Tools and Resources
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8313864/
https://ncbi.nlm.nih.gov/pubmed/34060624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.253484
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