An optogenetic method for interrogating YAP1 and TAZ nuclear–cytoplasmic shuttling

The shuttling of transcription factors and transcriptional regulators into and out of the nucleus is central to the regulation of many biological processes. Here we describe a new method for studying the rates of nuclear entry and exit of transcriptional regulators. A photo-responsive LOV (light–oxy...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Dowbaj, Anna M., Jenkins, Robert P., Williamson, Daniel, Heddleston, John M., Ciccarelli, Alessandro, Fallesen, Todd, Hahn, Klaus M., O'Dea, Reuben D., King, John R., Montagner, Marco, Sahai, Erik
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2021
Assuntos:
Tools and Resources
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8313864/
https://ncbi.nlm.nih.gov/pubmed/34060624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.253484
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