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New insights into YAP/TAZ nucleo‐cytoplasmic shuttling: new cancer therapeutic opportunities?

Yes‐associated protein (YAP) and transcriptional co‐activator with PDZ‐binding motif (TAZ), the main effectors of the Hippo pathway, are emerging as important players in cancer biology and therapy response. The intracellular localization of YAP/TAZ is a key determinant in the regulation of their act...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Shreberk‐Shaked, Michal, Oren, Moshe
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547617/
https://ncbi.nlm.nih.gov/pubmed/31050214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12498
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