Nucleo-cytoplasmic transport as a therapeutic target of cancer

Shuttling of specific proteins out of the nucleus is essential for the regulation of the cell cycle and proliferation of both normal and malignant tissues. Dysregulation of this fundamental process may affect many other important cellular processes such as tumor growth, inflammatory response, cell c...

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Bibliografiske detaljer
Udgivet i:J Hematol Oncol
Main Authors: Gravina, Giovanni Luca, Senapedis, William, McCauley, Dilara, Baloglu, Erkan, Shacham, Sharon, Festuccia, Claudio
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4272779/
https://ncbi.nlm.nih.gov/pubmed/25476752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-014-0085-1
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