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SUMOylation regulates nucleo-cytoplasmic shuttling of Elk-1
The transcription factor Elk-1 is a nuclear target of mitogen-activated protein kinases and regulates immediate early gene activation by extracellular signals. We show that Elk-1 is also conjugated to SUMO on either lysines 230, 249, or 254. Mutation of all three sites is necessary to fully block SU...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2172397/ https://ncbi.nlm.nih.gov/pubmed/15210726 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200310136 |
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