Down-Regulation of c-Fos/c-Jun AP-1 Dimer Activity by Sumoylation

The inducible transcriptional complex AP-1, composed of c-Fos and c-Jun proteins, is crucial for cell adaptation to many environmental changes. While its mechanisms of activation have been extensively studied, how its activity is restrained is poorly understood. We report here that lysine 265 of c-F...

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Detalhes bibliográficos
Main Authors: Bossis, Guillaume, Malnou, Cécile E., Farras, Rosa, Andermarcher, Elisabetta, Hipskind, Robert, Rodriguez, Manuel, Schmidt, Darja, Muller, Stefan, Jariel-Encontre, Isabelle, Piechaczyk, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190241/
https://ncbi.nlm.nih.gov/pubmed/16055710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.16.6964-6979.2005
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