Down-Regulation of c-Fos/c-Jun AP-1 Dimer Activity by Sumoylation

The inducible transcriptional complex AP-1, composed of c-Fos and c-Jun proteins, is crucial for cell adaptation to many environmental changes. While its mechanisms of activation have been extensively studied, how its activity is restrained is poorly understood. We report here that lysine 265 of c-F...

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Dettagli Bibliografici
Autori principali: Bossis, Guillaume, Malnou, Cécile E., Farras, Rosa, Andermarcher, Elisabetta, Hipskind, Robert, Rodriguez, Manuel, Schmidt, Darja, Muller, Stefan, Jariel-Encontre, Isabelle, Piechaczyk, Marc
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2005
Soggetti:
Gene Expression
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190241/
https://ncbi.nlm.nih.gov/pubmed/16055710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.16.6964-6979.2005
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