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Down-Regulation of c-Fos/c-Jun AP-1 Dimer Activity by Sumoylation
The inducible transcriptional complex AP-1, composed of c-Fos and c-Jun proteins, is crucial for cell adaptation to many environmental changes. While its mechanisms of activation have been extensively studied, how its activity is restrained is poorly understood. We report here that lysine 265 of c-F...
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| Главные авторы: | , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology
2005
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1190241/ https://ncbi.nlm.nih.gov/pubmed/16055710 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.16.6964-6979.2005 |
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