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Down-Regulation of c-Fos/c-Jun AP-1 Dimer Activity by Sumoylation

The inducible transcriptional complex AP-1, composed of c-Fos and c-Jun proteins, is crucial for cell adaptation to many environmental changes. While its mechanisms of activation have been extensively studied, how its activity is restrained is poorly understood. We report here that lysine 265 of c-F...

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Autors principals: Bossis, Guillaume, Malnou, Cécile E., Farras, Rosa, Andermarcher, Elisabetta, Hipskind, Robert, Rodriguez, Manuel, Schmidt, Darja, Muller, Stefan, Jariel-Encontre, Isabelle, Piechaczyk, Marc
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190241/
https://ncbi.nlm.nih.gov/pubmed/16055710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.16.6964-6979.2005
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