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c-Fos Proto-Oncoprotein Is Degraded by the Proteasome Independently of Its Own Ubiquitinylation In Vivo

Prior ubiquitinylation of the unstable c-Fos proto-oncoprotein is thought to be required for recognition and degradation by the proteasome. Contradicting this view, we report that, although c-Fos can form conjugates with ubiquitin in vivo, nonubiquitinylatable c-Fos mutants show regulated degradatio...

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Bibliografski detalji
Glavni autori: Bossis, Guillaume, Ferrara, Patrizia, Acquaviva, Claire, Jariel-Encontre, Isabelle, Piechaczyk, Marc
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2003
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC230311/
https://ncbi.nlm.nih.gov/pubmed/14517309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.20.7425-7436.2003
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