c-Fos Proto-Oncoprotein Is Degraded by the Proteasome Independently of Its Own Ubiquitinylation In Vivo

Prior ubiquitinylation of the unstable c-Fos proto-oncoprotein is thought to be required for recognition and degradation by the proteasome. Contradicting this view, we report that, although c-Fos can form conjugates with ubiquitin in vivo, nonubiquitinylatable c-Fos mutants show regulated degradatio...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Bossis, Guillaume, Ferrara, Patrizia, Acquaviva, Claire, Jariel-Encontre, Isabelle, Piechaczyk, Marc
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2003
Fag:
Gene Expression
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC230311/
https://ncbi.nlm.nih.gov/pubmed/14517309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.20.7425-7436.2003
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker