Down-Regulation of c-Fos/c-Jun AP-1 Dimer Activity by Sumoylation

The inducible transcriptional complex AP-1, composed of c-Fos and c-Jun proteins, is crucial for cell adaptation to many environmental changes. While its mechanisms of activation have been extensively studied, how its activity is restrained is poorly understood. We report here that lysine 265 of c-F...

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Hlavní autoři: Bossis, Guillaume, Malnou, Cécile E., Farras, Rosa, Andermarcher, Elisabetta, Hipskind, Robert, Rodriguez, Manuel, Schmidt, Darja, Muller, Stefan, Jariel-Encontre, Isabelle, Piechaczyk, Marc
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2005
Témata:
Gene Expression
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190241/
https://ncbi.nlm.nih.gov/pubmed/16055710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.16.6964-6979.2005
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