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Structural basis of substrate specificity in human cytidine deaminase family APOBEC3s
The human cytidine deaminase family of APOBEC3s (A3s) plays critical roles in both innate immunity and the development of cancers. A3s comprise seven functionally overlapping but distinct members that can be exploited as nucleotide base editors for treating genetic diseases. Although overall structu...
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| Pubblicato in: | J Biol Chem |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8313598/ https://ncbi.nlm.nih.gov/pubmed/34171358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100909 |
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