Characterization and Functional Analysis of CD44v6.CAR T Cells Endowed with a New Low-Affinity Nerve Growth Factor Receptor-Based Spacer

Effectiveness of adoptively transferred chimeric antigen receptor (CAR) T cells strongly depends on the quality of CAR-mediated interaction of the effector cells with the target antigen on tumor cells. A major role in this interaction is played by the affinity of the single-chain variable fragment (...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Hum Gene Ther
Main Authors: Stornaiuolo, Anna, Valentinis, Barbara, Sirini, Camilla, Scavullo, Cinzia, Asperti, Claudia, Zhou, Dan, Martinez De La Torre, Yeny, Corna, Stefano, Casucci, Monica, Porcellini, Simona, Traversari, Catia
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc., publishers 2021
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8312023/
https://ncbi.nlm.nih.gov/pubmed/33554732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2020.216
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki