Extracellular NGFR Spacers Allow Efficient Tracking and Enrichment of Fully Functional CAR-T Cells Co-Expressing a Suicide Gene

Chimeric antigen receptor (CAR)-T cell immunotherapy is at the forefront of innovative cancer therapeutics. However, lack of standardization of cellular products within the same clinical trial and lack of harmonization between different trials have hindered the clear identification of efficacy and s...

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Vydáno v:Front Immunol
Hlavní autoři: Casucci, Monica, Falcone, Laura, Camisa, Barbara, Norelli, Margherita, Porcellini, Simona, Stornaiuolo, Anna, Ciceri, Fabio, Traversari, Catia, Bordignon, Claudio, Bonini, Chiara, Bondanza, Attilio
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5871667/
https://ncbi.nlm.nih.gov/pubmed/29619024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00507
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