Extracellular NGFR Spacers Allow Efficient Tracking and Enrichment of Fully Functional CAR-T Cells Co-Expressing a Suicide Gene

Chimeric antigen receptor (CAR)-T cell immunotherapy is at the forefront of innovative cancer therapeutics. However, lack of standardization of cellular products within the same clinical trial and lack of harmonization between different trials have hindered the clear identification of efficacy and s...

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Bibliografske podrobnosti
izdano v:Front Immunol
Main Authors: Casucci, Monica, Falcone, Laura, Camisa, Barbara, Norelli, Margherita, Porcellini, Simona, Stornaiuolo, Anna, Ciceri, Fabio, Traversari, Catia, Bordignon, Claudio, Bonini, Chiara, Bondanza, Attilio
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018
Teme:
Immunology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5871667/
https://ncbi.nlm.nih.gov/pubmed/29619024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00507
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