Extracellular NGFR Spacers Allow Efficient Tracking and Enrichment of Fully Functional CAR-T Cells Co-Expressing a Suicide Gene

Chimeric antigen receptor (CAR)-T cell immunotherapy is at the forefront of innovative cancer therapeutics. However, lack of standardization of cellular products within the same clinical trial and lack of harmonization between different trials have hindered the clear identification of efficacy and s...

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Publicat a:Front Immunol
Autors principals: Casucci, Monica, Falcone, Laura, Camisa, Barbara, Norelli, Margherita, Porcellini, Simona, Stornaiuolo, Anna, Ciceri, Fabio, Traversari, Catia, Bordignon, Claudio, Bonini, Chiara, Bondanza, Attilio
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5871667/
https://ncbi.nlm.nih.gov/pubmed/29619024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00507
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