The tumor vessel targeting agent NGR-TNF controls the different stages of the tumorigenic process in transgenic mice by distinct mechanisms

NGR-TNF is a vascular targeting agent in advanced clinical development, coupling tumor necrosis factor-α (TNF) with the CNGRCG peptide, which targets a CD13 isoform specifically expressed by angiogenic vessels. Antitumor efficacy of NGR-TNF has been described in different transplantation tumor model...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Porcellini, Simona, Asperti, Claudia, Valentinis, Barbara, Tiziano, Elena, Mangia, Patrizia, Bordignon, Claudio, Rizzardi, Gian-Paolo, Traversari, Catia
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589061/
https://ncbi.nlm.nih.gov/pubmed/26451306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1041700
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