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Distinctive Properties and Powerful Neuromodulation of Na(v)1.6 Sodium Channels Regulates Neuronal Excitability

Voltage-gated sodium channels (Navs) are critical determinants of cellular excitability. These ion channels exist as large heteromultimeric structures and their activity is tightly controlled. In neurons, the isoform Na(v)1.6 is highly enriched at the axon initial segment and nodes, making it critic...

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Bibliografische gegevens
Gepubliceerd in:Cells
Hoofdauteurs: Zybura, Agnes, Hudmon, Andy, Cummins, Theodore R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8307729/
https://ncbi.nlm.nih.gov/pubmed/34202119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10071595
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