Distinct repriming and closed-state inactivation kinetics of Na(v)1.6 and Na(v)1.7 sodium channels in mouse spinal sensory neurons

While large, myelinated dorsal root ganglion (DRG) neurons are capable of firing at high frequencies, small unmyelinated DRG neurons typically display much lower maximum firing frequencies. However, the molecular basis for this difference has not been delineated. Because the sodium currents in large...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Herzog, Raimund I, Cummins, Theodore R, Ghassemi, Farshid, Dib-Hajj, Sulayman D, Waxman, Stephen G
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Inc 2003
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2343279/
https://ncbi.nlm.nih.gov/pubmed/12843211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2003.047357
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