Učitavanje...
Structural Basis for the Modulation of the Neuronal Voltage-Gated Sodium Channel Na(V)1.6 by Calmodulin
The neuronal-voltage gated sodium channel (VGSC), Na(V)1.6, plays an important role in propagating action potentials along myelinated axons. Calmodulin (CaM) is known to modulate the inactivation kinetics of Na(V)1.6 by interacting with its IQ motif. Here we report the crystal structure of apo-CaM:N...
Spremljeno u:
| Glavni autori: | , , , , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2013
|
| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3743062/ https://ncbi.nlm.nih.gov/pubmed/23942337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02435 |
| Oznake: |
Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!
|