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Modulation of skeletal and cardiac voltage-gated sodium channels by calmodulin

Calmodulin (CaM) has been shown to modulate different ion channels, including voltage-gated sodium channels (NaChs). Using the yeast two-hybrid assay, we found an interaction between CaM and the C-terminal domains of adult skeletal (Na(V)1.4) and cardiac (Na(V)1.5) muscle NaChs. Effects of CaM were...

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Autori principali: Young, Katharine A, Caldwell, John H
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1464525/
https://ncbi.nlm.nih.gov/pubmed/15746172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.081422
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