Tumor Escape Phenotype in Bladder Cancer Is Associated with Loss of HLA Class I Expression, T-Cell Exclusion and Stromal Changes

Cancer eradication and clinical outcome of immunotherapy depend on tumor cell immunogenicity, including HLA class I (HLA-I) and PD-L1 expression on malignant cells, and on the characteristics of the tumor microenvironment, such as tumor immune infiltration and stromal reaction. Loss of tumor HLA-I i...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Int J Mol Sci
Prif Awduron: Gil-Julio, Hernani, Perea, Francisco, Rodriguez-Nicolas, Antonio, Cozar, Jose Manuel, González-Ramirez, Amanda Rocío, Concha, Angel, Garrido, Federico, Aptsiauri, Natalia, Ruiz-Cabello, Francisco
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2021
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8307653/
https://ncbi.nlm.nih.gov/pubmed/34298868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22147248
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