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Cancer immune escape: MHC expression in primary tumours versus metastases

Tumours can escape T‐cell responses by losing major histocompatibility complex (MHC)/ human leucocyte antigen (HLA) class I molecules. In the early stages of cancer development, primary tumours are composed of homogeneous HLA class I‐positive cancer cells. Subsequently, infiltration of the tumour by...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Garrido, Federico, Aptsiauri, Natalia
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6856929/
https://ncbi.nlm.nih.gov/pubmed/31509607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.13114
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