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The Escape of Cancer from T Cell-Mediated Immune Surveillance: HLA Class I Loss and Tumor Tissue Architecture

Tumor immune escape is associated with the loss of tumor HLA class I (HLA-I) expression commonly found in malignant cells. Accumulating evidence suggests that the efficacy of immunotherapy depends on the expression levels of HLA class I molecules on tumors cells. It also depends on the molecular mec...

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Detalhes bibliográficos
Publicado no:Vaccines (Basel)
Main Authors: Garrido, Federico, Perea, Francisco, Bernal, Mónica, Sánchez-Palencia, Abel, Aptsiauri, Natalia, Ruiz-Cabello, Francisco
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5371743/
https://ncbi.nlm.nih.gov/pubmed/28264447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines5010007
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