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Distinct mechanisms of loss of IFN-gamma mediated HLA class I inducibility in two melanoma cell lines

BACKGROUND: The inability of cancer cells to present antigen on the cell surface via MHC class I molecules is one of the mechanisms by which tumor cells evade anti-tumor immunity. Alterations of Jak-STAT components of interferon (IFN)-mediated signaling can contribute to the mechanism of cell resist...

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Main Authors: Rodríguez, Teresa, Méndez, Rosa, Del Campo, Ana, Jiménez, Pilar, Aptsiauri, Natalia, Garrido, Federico, Ruiz-Cabello, Francisco
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2007
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1808467/
https://ncbi.nlm.nih.gov/pubmed/17319941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-7-34
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