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HLA class I loss in colorectal cancer: implications for immune escape and immunotherapy

T cell-mediated immune therapies have emerged as a promising treatment modality in different malignancies including colorectal cancer (CRC). However, only a fraction of patients currently respond to treatment. Understanding the lack of responses and finding biomarkers with predictive value is of gre...

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Bibliographic Details
Published in:Cell Mol Immunol
Main Authors: Anderson, Per, Aptsiauri, Natalia, Ruiz-Cabello, Francisco, Garrido, Federico
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2021
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8027055/
https://ncbi.nlm.nih.gov/pubmed/33473191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41423-021-00634-7
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