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Cholesterol is required for transcriptional repression by BASP1

Lipids are present within the cell nucleus, where they engage with factors involved in gene regulation. Cholesterol associates with chromatin in vivo and stimulates nucleosome packing in vitro, but its effects on specific transcriptional responses are not clear. Here, we show that the lipidated Wilm...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Proc Natl Acad Sci U S A
Κύριοι συγγραφείς: Loats, Amy E., Carrera, Samantha, Fleming, Anna F., Roberts, Abigail R. E., Sherrard, Alice, Toska, Eneda, Moorhouse, Alexander J., Medler, Kathryn F., Roberts, Stefan G. E.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: National Academy of Sciences 2021
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8307447/
https://ncbi.nlm.nih.gov/pubmed/34266955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2101671118
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