Cholesterol is required for transcriptional repression by BASP1

Lipids are present within the cell nucleus, where they engage with factors involved in gene regulation. Cholesterol associates with chromatin in vivo and stimulates nucleosome packing in vitro, but its effects on specific transcriptional responses are not clear. Here, we show that the lipidated Wilm...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Loats, Amy E., Carrera, Samantha, Fleming, Anna F., Roberts, Abigail R. E., Sherrard, Alice, Toska, Eneda, Moorhouse, Alexander J., Medler, Kathryn F., Roberts, Stefan G. E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2021
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8307447/
https://ncbi.nlm.nih.gov/pubmed/34266955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2101671118
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