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Prohibitin is required for transcriptional repression by the WT1-BASP1 complex

The Wilms’ tumor 1 protein (WT1) is a transcriptional regulator that can either activate or repress genes controlling cell growth, apoptosis and differentiation. The transcriptional corepressor BASP1 interacts with WT1 and mediates WT1's transcriptional repression activity. BASP1 is contained w...

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Bibliographic Details
Main Authors: Toska, Eneda, Shandilya, Jayasha, Goodfellow, Sarah J., Medler, Kathryn F., Roberts, Stefan G. E.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002674/
https://ncbi.nlm.nih.gov/pubmed/24166496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.447
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