Repression of Transcription by WT1-BASP1 Requires the Myristoylation of BASP1 and the PIP2-Dependent Recruitment of Histone Deacetylase

The Wilms’ tumor 1 protein WT1 is a transcriptional regulator that is involved in cell growth and differentiation. The transcriptional corepressor BASP1 interacts with WT1 and converts WT1 from a transcriptional activator to a repressor. Here, we demonstrate that the N-terminal myristoylation of BAS...

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Библиографические подробности
Главные авторы: Toska, Eneda, Campbell, Hayley A., Shandilya, Jayasha, Goodfellow, Sarah J., Shore, Paul, Medler, Kathryn F., Roberts, Stefan G.E.
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500702/
https://ncbi.nlm.nih.gov/pubmed/22939983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.08.005
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