WWOX and Its Binding Proteins in Neurodegeneration

WW domain-containing oxidoreductase (WWOX) is known as one of the risk factors for Alzheimer’s disease (AD), a neurodegenerative disease. WWOX binds Tau via its C-terminal SDR domain and interacts with Tau phosphorylating enzymes ERK, JNK, and GSK-3β, and thereby limits AD progression. Loss of WWOX...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Cells
Autori principali: Hsu, Che-Yu, Lee, Kuan-Ting, Sun, Tzu-Yu, Sze, Chun-I., Huang, Shenq-Shyang, Hsu, Li-Jin, Chang, Nan-Shan
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
Soggetti:
Review
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8304785/
https://ncbi.nlm.nih.gov/pubmed/34359949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10071781
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi