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WWOX Phosphorylation, Signaling, and Role in Neurodegeneration
Homozygous null mutation of tumor suppressor WWOX/Wwox gene leads to severe neural diseases, metabolic disorders and early death in the newborns of humans, mice and rats. WWOX is frequently downregulated in the hippocampi of patients with Alzheimer’s disease (AD). In vitro analysis revealed that kno...
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| 出版年: | Front Neurosci |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Frontiers Media S.A.
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6104168/ https://ncbi.nlm.nih.gov/pubmed/30158849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00563 |
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