HYAL-2–WWOX–SMAD4 Signaling in Cell Death and Anticancer Response

Hyaluronidase HYAL-2 is a membrane-anchored protein and also localizes, in part, in the lysosome. Recent study from animal models revealed that both HYAL-1 and HYAL-2 are essential for the metabolism of hyaluronan (HA). Hyal-2 deficiency is associated with chronic thrombotic microangiopathy with hem...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Hsu, Li-Jin, Chiang, Ming-Fu, Sze, Chun-I, Su, Wan-Pei, Yap, Ye Vone, Lee, I-Ting, Kuo, Hsiang-Ling, Chang, Nan-Shan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5138198/
https://ncbi.nlm.nih.gov/pubmed/27999774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2016.00141
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