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Role of WWOX and NF-κB in lung cancer progression
It is generally agreed that the pro-inflammatory, pro-survival transcription factor NF-κB is a tumor promoter. Tumor necrosis factor alpha (TNF-α or TNF) mediates NF-κB activation. Tumor suppressor WWOX (FOR or WOX1) is a downstream effector of the TNF signaling. Thus, activation of both WWOX (FOR o...
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| Publié dans: | Transl Respir Med |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Springer Berlin Heidelberg
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4715152/ https://ncbi.nlm.nih.gov/pubmed/27234396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2213-0802-1-15 |
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