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Role of WWOX and NF-κB in lung cancer progression

It is generally agreed that the pro-inflammatory, pro-survival transcription factor NF-κB is a tumor promoter. Tumor necrosis factor alpha (TNF-α or TNF) mediates NF-κB activation. Tumor suppressor WWOX (FOR or WOX1) is a downstream effector of the TNF signaling. Thus, activation of both WWOX (FOR o...

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Publicat a:Transl Respir Med
Autors principals: Chen, Szu-Jung, Huang, Shenq-Shyang, Chang, Nan-Shan
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715152/
https://ncbi.nlm.nih.gov/pubmed/27234396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2213-0802-1-15
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