Disruption of GPR35 Signaling in Bone Marrow-Derived Cells Does Not Influence Vascular Inflammation and Atherosclerosis in Hyperlipidemic Mice

G-protein-coupled receptor-35 (GPR35) has been identified as a receptor for the tryptophan metabolite kynurenic acid (KynA) and suggested to modulate macrophage polarization in metabolic tissues. Whether GPR35 can influence vascular inflammation and atherosclerosis has however never been tested. Let...

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Pubblicato in:Metabolites
Autori principali: Baumgartner, Roland, Casagrande, Felipe B., Mikkelsen, Randi B., Berg, Martin, Polyzos, Konstantinos A., Forteza, Maria J., Arora, Aastha, Schwartz, Thue W., Hjorth, Siv A., Ketelhuth, Daniel F. J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8303390/
https://ncbi.nlm.nih.gov/pubmed/34201526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/metabo11070411
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