Disruption of GPR35 Signaling in Bone Marrow-Derived Cells Does Not Influence Vascular Inflammation and Atherosclerosis in Hyperlipidemic Mice

G-protein-coupled receptor-35 (GPR35) has been identified as a receptor for the tryptophan metabolite kynurenic acid (KynA) and suggested to modulate macrophage polarization in metabolic tissues. Whether GPR35 can influence vascular inflammation and atherosclerosis has however never been tested. Let...

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Veröffentlicht in:Metabolites
Hauptverfasser: Baumgartner, Roland, Casagrande, Felipe B., Mikkelsen, Randi B., Berg, Martin, Polyzos, Konstantinos A., Forteza, Maria J., Arora, Aastha, Schwartz, Thue W., Hjorth, Siv A., Ketelhuth, Daniel F. J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8303390/
https://ncbi.nlm.nih.gov/pubmed/34201526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/metabo11070411
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