The immunodominant antibody response to Zika virus NS1 protein is characterized by cross-reactivity to self

Besides antigen-specific responses to viral antigens, humoral immune response in virus infection can generate polyreactive and autoreactive antibodies. Dengue and Zika virus infections have been linked to antibody-mediated autoimmune disorders, including Guillain-Barré syndrome. A unique feature of...

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Publicado en:J Exp Med
Main Authors: Cavazzoni, Cecilia B., Bozza, Vicente B.T., Lucas, Tostes C.V., Conde, Luciana, Maia, Bruno, Mesin, Luka, Schiepers, Ariën, Ersching, Jonatan, Neris, Romulo L.S., Conde, Jonas N., Coelho, Diego R., Lima, Tulio M., Alvim, Renata G.F., Castilho, Leda R., de Paula Neto, Heitor A., Mohana-Borges, Ronaldo, Assunção-Miranda, Iranaia, Nobrega, Alberto, Victora, Gabriel D., Vale, Andre M.
Formato: Artigo
Idioma:Inglês
Publicado: Rockefeller University Press 2021
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8302445/
https://ncbi.nlm.nih.gov/pubmed/34292314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20210580
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