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CLONAL AND CELLULAR DYNAMICS IN GERMINAL CENTERS
Germinal centers (GCs) are the site of antibody affinity maturation, a process that involves complex clonal and cellular dynamics. Selection of B cells bearing higher-affinity immunoglobulins proceeds via a stereotyped pattern where B cells migrate cyclically between the GC’s two anatomical compartm...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4037377/ https://ncbi.nlm.nih.gov/pubmed/24681449 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2014.02.010 |
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