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CLONAL AND CELLULAR DYNAMICS IN GERMINAL CENTERS

Germinal centers (GCs) are the site of antibody affinity maturation, a process that involves complex clonal and cellular dynamics. Selection of B cells bearing higher-affinity immunoglobulins proceeds via a stereotyped pattern where B cells migrate cyclically between the GC’s two anatomical compartm...

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Bibliografiske detaljer
Main Authors: Victora, Gabriel D., Mesin, Luka
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037377/
https://ncbi.nlm.nih.gov/pubmed/24681449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2014.02.010
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