A Population Dynamics Model for Clonal Diversity in a Germinal Center

Germinal centers (GCs) are micro-domains where B cells mature to develop high affinity antibodies. Inside a GC, B cells compete for antigen and T cell help, and the successful ones continue to evolve. New experimental results suggest that, under identical conditions, a wide spectrum of clonal divers...

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Bibliografiske detaljer
Udgivet i:Front Microbiol
Main Authors: Amitai, Assaf, Mesin, Luka, Victora, Gabriel D., Kardar, Mehran, Chakraborty, Arup K.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600966/
https://ncbi.nlm.nih.gov/pubmed/28955307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.01693
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