The immunodominant antibody response to Zika virus NS1 protein is characterized by cross-reactivity to self

Besides antigen-specific responses to viral antigens, humoral immune response in virus infection can generate polyreactive and autoreactive antibodies. Dengue and Zika virus infections have been linked to antibody-mediated autoimmune disorders, including Guillain-Barré syndrome. A unique feature of...

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Publicat a:J Exp Med
Autors principals: Cavazzoni, Cecilia B., Bozza, Vicente B.T., Lucas, Tostes C.V., Conde, Luciana, Maia, Bruno, Mesin, Luka, Schiepers, Ariën, Ersching, Jonatan, Neris, Romulo L.S., Conde, Jonas N., Coelho, Diego R., Lima, Tulio M., Alvim, Renata G.F., Castilho, Leda R., de Paula Neto, Heitor A., Mohana-Borges, Ronaldo, Assunção-Miranda, Iranaia, Nobrega, Alberto, Victora, Gabriel D., Vale, Andre M.
Format: Artigo
Idioma:Inglês
Publicat: Rockefeller University Press 2021
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8302445/
https://ncbi.nlm.nih.gov/pubmed/34292314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20210580
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