Pitfalls of NMDA Receptor Modulation by Neuroactive Steroids. The Effect of Positive and Negative Modulation of NMDA Receptors in an Animal Model of Schizophrenia

Evidence from clinical and preclinical studies implicates dysfunction of N-methyl-D-aspartate receptors (NMDARs) in schizophrenia progression and symptoms. We investigated the antipsychotic effect of two neuroactive steroids in an animal model of schizophrenia induced by systemic application of MK-8...

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Bibliografiske detaljer
Udgivet i:Biomolecules
Main Authors: Holubova, Kristina, Chvojkova, Marketa, Hrcka Krausova, Barbora, Vyklicky, Vojtech, Kudova, Eva, Chodounska, Hana, Vyklicky, Ladislav, Vales, Karel
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8301783/
https://ncbi.nlm.nih.gov/pubmed/34356650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11071026
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