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Pitfalls of NMDA Receptor Modulation by Neuroactive Steroids. The Effect of Positive and Negative Modulation of NMDA Receptors in an Animal Model of Schizophrenia

Evidence from clinical and preclinical studies implicates dysfunction of N-methyl-D-aspartate receptors (NMDARs) in schizophrenia progression and symptoms. We investigated the antipsychotic effect of two neuroactive steroids in an animal model of schizophrenia induced by systemic application of MK-8...

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Detaylı Bibliyografya
Yayımlandı:Biomolecules
Asıl Yazarlar: Holubova, Kristina, Chvojkova, Marketa, Hrcka Krausova, Barbora, Vyklicky, Vojtech, Kudova, Eva, Chodounska, Hana, Vyklicky, Ladislav, Vales, Karel
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8301783/
https://ncbi.nlm.nih.gov/pubmed/34356650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11071026
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