A functional taxonomy of tumor suppression in oncogenic KRAS-driven lung cancer

Cancer genotyping has identified a large number of putative tumor suppressor genes. Carcinogenesis is a multi-step process, however the importance and specific roles of many of these genes during tumor initiation, growth and progression remain unknown. Here we use a multiplexed mouse model of oncoge...

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Dettagli Bibliografici
Pubblicato in:Cancer Discov
Autori principali: Cai, Hongchen, Chew, Su Kit, Li, Chuan, Tsai, Min K., Andrejka, Laura, Murray, Christopher W., Hughes, Nicholas W., Shuldiner, Emily G., Ashkin, Emily L., Tang, Rui, Hung, King L., Chen, Leo C., Lee, Shi Ya C., Yousefi, Maryam, Lin, Wen-Yang, Kunder, Christian A., Cong, Le, McFarland, Christopher D., Petrov, Dmitri A., Swanton, Charles, Winslow, Monte M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8292166/
https://ncbi.nlm.nih.gov/pubmed/33608386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-20-1325
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