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A functional taxonomy of tumor suppression in oncogenic KRAS-driven lung cancer

Cancer genotyping has identified a large number of putative tumor suppressor genes. Carcinogenesis is a multi-step process, however the importance and specific roles of many of these genes during tumor initiation, growth and progression remain unknown. Here we use a multiplexed mouse model of oncoge...

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Detalhes bibliográficos
Publicado no:Cancer Discov
Main Authors: Cai, Hongchen, Chew, Su Kit, Li, Chuan, Tsai, Min K., Andrejka, Laura, Murray, Christopher W., Hughes, Nicholas W., Shuldiner, Emily G., Ashkin, Emily L., Tang, Rui, Hung, King L., Chen, Leo C., Lee, Shi Ya C., Yousefi, Maryam, Lin, Wen-Yang, Kunder, Christian A., Cong, Le, McFarland, Christopher D., Petrov, Dmitri A., Swanton, Charles, Winslow, Monte M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8292166/
https://ncbi.nlm.nih.gov/pubmed/33608386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-20-1325
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