ADME gene polymorphisms do not influence the pharmacokinetics of docetaxel: Results from a population pharmacokinetic study in Indian cancer patients

BACKGROUND: Pharmacokinetics (PK) of docetaxel is characterized by high inter‐individual variability (IIV). While covariate models that explain the PK variability of docetaxel exist, not much is known about the effects of genetic variations on docetaxel disposition. METHODS: Fifty patients with head...

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發表在:Cancer Med
Main Authors: Patil, Anand, Shriyan, Bharati, Mehta, Parsshava, Patil, Mrudula, Gurjar, Murari, Nookala, Manjunath, Patil, Vijay, Joshi, Amit, Noronha, Vanita, Prabhash, Kumar, Gota, Vikram
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2021
主題:
Cancer Prevention
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8290241/
https://ncbi.nlm.nih.gov/pubmed/34156160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.4026
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