ADME gene polymorphisms do not influence the pharmacokinetics of docetaxel: Results from a population pharmacokinetic study in Indian cancer patients

BACKGROUND: Pharmacokinetics (PK) of docetaxel is characterized by high inter‐individual variability (IIV). While covariate models that explain the PK variability of docetaxel exist, not much is known about the effects of genetic variations on docetaxel disposition. METHODS: Fifty patients with head...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Patil, Anand, Shriyan, Bharati, Mehta, Parsshava, Patil, Mrudula, Gurjar, Murari, Nookala, Manjunath, Patil, Vijay, Joshi, Amit, Noronha, Vanita, Prabhash, Kumar, Gota, Vikram
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Cancer Prevention
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8290241/
https://ncbi.nlm.nih.gov/pubmed/34156160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.4026
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